PRE-PRINT: Non-permissive SARS-CoV-2 infection of neural cells in the developing human brain and neurospheres

by Carolina da S. G. Pedrosa et al.

Coronavirus disease 2019 (COVID-19) was initially described as a viral infection of the respiratory tract. It is now known, however, that many other biological systems are affected, including the central nervous system (CNS). Neurological manifestations such as stroke, encephalitis, and psychiatric conditions have been reported in COVID-19 patients, but its neurotropic potential is still debated. Here, we investigate the presence of SARS-CoV-2 in the brain from an infant patient deceased from COVID-19.  FULL TEXT

2nd October 2020 • comment